expression of fission 1 protein in cortical neurons of rats with chronic fluorosis] our most valuable

Fluoride Action Network | Fluoridation of drinking water and chronic kidney disease: Absence of evidence is

Fluoride Action Network | Effect of concurrent chronic exposure of fluoride and aluminum on rat brain

Fluoride Action Network | Effect of different doses of chronic exposure of fluoride on rat learning

nAChRs and ERK1/2 in the brains of rats with chronic fluorosis and their

Fluoride Action Network | Chronic administration of aluminum-fluoride or sodium-fluoride to rats in drinking

in drinking water and diet: the causative factor of chronic kidney diseases in

of thyroid function in humans under the conditions of chronic occupational exposure to

vacuolization of both auricle and ventricle regions on exposure to chronic fluoride.” SOURCE: Basha MP

and tracing several diseases from past to present times. Skeletal fluorosis, a chronic metabolic bone and

1977). A study, however, of children found that those with dental fluorosis (indicating chronic fluoride overexposure) had lower

in the vitamin C and G. biloba groups. To conclude chronic exposure to high

Fluoride Poisoning: “[A] fairly substantial body of research indicates that patients with chronic renal insufficiency are at

fluoride intake in patients with stages 4 and 5 of chronic kidney diseases and

et al., 1983). Altered ECG readings have also been observed in experimental animals with chronic and subacute

for dense lumbar vertebras Painful periostitis in the setting of chronic voriconazole therapy A

Kidney Patients) “[A] fairly substantial body of research indicates that patients with chronic renal insufficiency are at

Changes in serum seromucoid following compensatory hyperparathyroidism: A sequel to chronic fluoride ingestion. Indian Journal

This study was designed to evaluate adverse health effects in adolescents from chronic exposure to various

typical exposures of 8 mg/day. (Jolly 1970). As already noted, fluoride can cause chronic joint pain prior to

C-peptide contents in the blood serum of people during CFI [chronic fluoride intoxication], which evidenced

the mechanism of neurone apoptosis in rats from the chronic fluorosis]. Objective: Study the

consideration in view of the fact that radiologic evidence of chronic fluorosis has been found

at the two highest doses. Related Studies : The Effect of Chronic Fluorosis on Calcium Ions

Chemical and Engineering News August 1, 1988, 26-42. “It should also be noted that chronic fluorosis is not easily

Kidney Function: “[A] fairly substantial body of research indicates that patients with chronic renal insufficiency are at

expression of fission 1 protein in cortical neurons of rats with chronic fluorosis ]. [Article in

to think or assume and I think can safely be stated here that chronic fluorosis has a

Clinic from May 1, 1997, to July 1, 2006, whose bone disorders resulted from chronic fluoride exposure due to

American woman who developed SF from brewed tea. . . .Our patient had elevated bone mineral density . . ., severe chronic bone and joint

that fluoride causes to bone Fluoridation of drinking water and chronic kidney disease: Absence of

changes in serum glucose concentrations. Dunipace et al. (1995, 1998) found no significant differences with chronic fluoride treatment in

RNA contents of heart, liver and kidney of rats with chronic fluorosis 17 rats with

to reveal the mechanism of the brain injury induced by chronic fluorosis, the levels

since the intital stage, like that of many other kinds of chronic poisoning, develops slowly and

supplement, by weight. . . . If this same fluoride-to-calcium proportionality applies to chronic daily intake of

the mechanism of neurone apoptosis in rats from the chronic fluorosis]. Objective: Study the

death. The debate today, however, is not about fluoride’s acute toxicity, but its chronic toxicity (i.e., the

Teotia SPS, et al. (1976). Symposium on the Non-Skeletal Phase of Chronic Fluorosis: The Joints

the U.S. Department of Health and Human Services, too much fluoride causes “chronic joint pain” and

fluoride exposures may be contributing to neurological disorders, endocrine problems, and other chronic health ailments, the

and one at dorsal level) due to vertebral osteosclerosis secondary to chronic fluoride intoxication. Roentgenograms showed

the aorta is undergoing mineralization.” SOURCE: Susheela AK, Kharb P. (1990). Aortic calcification in chronic fluoride poisoning: biochemical and

factor in the development of enamel defects in children with [chronic renal failure], since the

1996). Inorganic fluoride kinetics and renal tubular function after sevoflurane anesthesia in chronic renal failure patients receiving

However, a study of children found that those with dental fluorosis (indicating chronic fluoride overexposure) had lower

2/111/63167 “Objective: To investigate the adverse effect of chronic fluorosis on the

fluoride.” SOURCE: Ailani V, et al. (2009). Oxidative stress in cases of chronic fluoride intoxication. Indian Journal

can increase the levels of glucose in the blood. Chronic elevation of blood

Connett A chemical’s toxicity can be measured in two basic ways: (1) chronic toxicity and (2

and Coplan that the EPA has no information on health effects of chronic ingestion of SiF

of glucose in the blood, as occurs in diabetes mellitus, chronic elevated blood sugar (hyperglycemia

and one at dorsal level) due to vertebral osteosclerosis secondary to chronic fluoride intoxication. Roentgenograms showed

receptor genes.  Toxicology  200: 169-77. 6) Guan ZZ, et al (1998). Influence of chronic fluorosis on membrane lipids

hyperostosis , osteoporosis , osteomalacia , and rickets .'” SOURCE: Krook L, Maylin GA. (1979). Industrial fluoride pollution. Chronic fluoride poisoning in

have been reported in bones which were ‘normal’… But bones from patients with severe chronic fluorosis have been found

acute toxic hazard, such as to people with  impaired kidney function , as well as chronic toxic hazards of

Lawrence Blake, 65, of Arundel Fluoridation of drinking water and chronic kidney disease: Absence of

a corresponding increase in urinary fluoride, indicating that these pregnant women were suffering from chronic fluoride poisoning. The

diseases simulating radiographic features of fluorosis are Paget’s disease, parathyroid hormone disorders, osteopetrosis, chronic renal failure, myelofibrosis, hypophosphatemic

of skeletal fluorosis. American Journal of Physical Anthropology 109: 465-483. “Persons with chronic renal failures constitute a

the non-fluoridated group… This study has shown that hemodialysis with fluoridated water in chronic renal failure induces the

low-grade food during 2-5 months under conditions of acute and chronic action of hydrogen

Kidney Disease “A fairly substantial body of research indicates that patients with chronic renal insufficiency are at

no evidence from this study that aging reduces the threshold of safe chronic fluoride exposure.” SOURCE: Dunipace

and withdrawal of organic matrix and water. It is evident that high chronic levels of fluoride

SOURCE: Lough J, et al. (1975). Effects of fluoride on bone in chronic renal failure. Archives of

Black Americans, for example, are  over two times as likely to develop chronic kidney disease and

ability to regulate blood glucose levels falters, as occurs in diabetes mellitus, chronic elevated glucose levels (hyperglycemia

in the controls. Histological examination of the gastric antral biopsy showed chronic atrophic gastritis in

studies are needed on fluoride concentrations in soft tissues (e.g., brain, thyroid, kidney) following chronic exposure.” p83 “Research is

3 and 9% respectively) was significantly increased compared with Genotoxic evaluation of chronic fluoride exposure: micronucleus and

i) oxidative stress Toxicity assessment of sodium fluoride in Drosophila melanogaster after chronic sub-lethal exposure Sodium

the short-term and long-term health effects that may be caused by chronic exposure to fluoridated

that may be associated with dementia. Consideration should be given to assessing effects from chronic exposure, effects that might

increase of the TSH level are observed in cases of chronic fluorine intoxication in

disfiguring brown and black staining of the teeth, which can cause chronic embarrassment and social

drinking water are not those usually associated with significant fluorosis.” SOURCE: Sauerbrunn BJ, et al. (1965). Chronic fluoride intoxication with fluorotic

of Skeletal Fluorosis Can Closely Resemble Osteoarthritis The symptoms of skeletal fluorosis (chronic joint pain and

from cellular toxic effect of NaF.” SOURCE: Snow GR, Anderson C. (1986). Short-term chronic fluoride administration and

and neonatal period may result in the development Effects of chronic fluoride exposure on object

disfiguring brown and black staining of the teeth, which can cause chronic embarrassment and social

to high fluoride: amelioration by Panax ginseng (Ginseng) and Lagerstroemia speciosa (Banaba) extracts Chronic fluoride intoxication results in

low-grade food during 2-5 months under conditions of acute and chronic action of hydrogen

increase of the TSH level are observed in cases of chronic fluorine intoxication in

of the study was to evaluate the influence of chronic exposure to fluoride

causes synaptic impairment contributing to fluoride–induced developmental neurotoxicity Highlights Rats were long–term chronic exposed to environmentally

disfiguring brown and black staining of the teeth, which can cause chronic  embarrassment and social

was likewise affected, a condition which he termed mottled dentin.” SOURCE: Dean HT. (1936). Chronic endemic dental fluorosis (mottled

levels of anti-oxidants in their blood; higher rates of chronic kidney disease; and

new paradigm STUDY BACKGROUND:  Fluorosis is one of the manifestations of chronic poisoning from long-term

report concludes. The Hooper Bay episode highlights a number of chronic, widespread problems that plague

November 27. Connecticut  –  Statewide mandatory fluoridation since 1960s: “Dental decay remains the most common chronic disease among Connecticut’s

into the systemic circulation–amounts which may be sufficient to produce acute or chronic side-effects.” SOURCE: Ekstrand

halide on the joints which are most used.” SOURCE: Anand JK, Roberts JT. (1990). Chronic fluorine poisoning in

report, three critical bodies analysed the public health benefits and risks from chronic F-exposure by reviewing

for the fact that, even though native intelligence per se may not be altered by chronic ingestion of water

Cinar and Selcuk 2005) have also been reported in cows diagnosed with chronic fluorosis in India

fluoride to have moderate to high acute toxicity from inhalation exposure.( 6 ) Chronic Effects (Noncancer): Chronic exposure

1985). Study on serum T4, T3, and TSH levels in patients with chronic skeletal fluorosis .  Chinese Journal