Fluoride Action Network | Thyroid function, intelligence, and low-moderate fluoride exposure among Chinese school-age children. our most valuable

body fluorine of healthy persons and thyroidopathy patients on the function of hypophyseal

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The reported results on the study of the iodine absorption function of the

System “In summary, evidence of several types indicates that fluoride affects normal endocrine function or response; the

population being studied. It is known, for example, that fluoride’s effect on thyroid function and neurological

effect of water containing 1 p.p.m. upon patients with severe impairment of kidney function requires special consideration in

SYSTEM: “In summary, evidence of several types indicates that fluoride affects normal endocrine function or response; the

Environmental Science and Technology 36:433–487 “In patients with reduced renal function, the potential

Thyroid “The effects of fluoride on various aspects of endocrine function should be examined, particularly

doctors in Europe and South America prescribed fluoride to reduce thyroid function in patients

that need the presence of the fluoride ion to function properly. On the

and 5% of the U.S. population may be affected by deranged thyroid function (Goodman 2003), making it

and emerging health parameters of interest (e.g.,  endocrine effects  and  brain function ) should be performed in

2020 Volume/Page: 134:105315. [Pre-published Nov 16, 2019] Type: Human Study Categories: Brain , Cognitive Function , Total Body Burden , Sources

Teratology 42(6):30A. Nishiyama et al. (1996). Inorganic fluoride kinetics and renal tubular function after sevoflurane anesthesia in

The concentrations of fluoride in human bone as a function of exposure

alter electrical activity, and thus altered ECG readings can indicate underlying problems with heart function. ECGs can help diagnose

SYSTEM: “In summary, evidence of several types indicates that fluoride affects normal endocrine function or response; the

Fluoride & Arterial Calcification Fluoride & Arteriosclerosis Fluoride & Electrocardiogram Abnormalities Fluoride & Myocardial Damage Endocrine Function Glucose Metabolism Fluoride &

total of 400 pediatric Effects of fluoride on growth and thyroid function in young

early years of life. Excessive intake of iodine can also impair thyroid function, causing hypothyroidism and

to cause decreased melatonin production and to have other effects on normal pineal function, which in turn

Date: April-June 2008 Volume/Page: 41(2):156–60. Type: Human Study Categories: Brain , Cognitive Function , Susceptible Populations , Nutritional Status

Suketa et al. (1985) attributed these increases to fluoride stimulation of adrenal function. Rigalli et al. (1990

fluoridation of community water actually causes kidney disease. Kidney damage to tubular function and structure

fluoride (F–) consumption [Joint effects of excessive fluoride and iodine on thyroid function among children in

order to explore the effects of excess fluoride on reproductive function of male

deficit hyperactivity disorder seem to be increasing worldwide. Subclinical decrements in brain function are even more common

of bone pain and did not experience further fractures. In 1971, renal function temporarily deteriorated further. After

Date: September 20, 2010 Volume/Page: 29(5):547-48. Type: Human Study Categories: Brain , Cognitive Function , IQ Score , *NTP2019 , Endemic

Publish Date: January 1991 Volume/Page: 7(3):24-25. Type: Human Study Categories: Brain , Cognitive Function , Susceptible Populations , Nutritional Status

Publish Date: January 1994 Volume/Page: 9(2):83-84. Type: Human Study Categories: Brain , Cognitive Function , Susceptible Populations , Nutritional Status

the factors that are believed to play a role: Impaired kidney function Polydipsia (Excessive thirst) Dietary

recommendations by many dental researchers that infants should not consume fluoridated water); individuals with poor kidney function (despite their impaired ability

brain and central nervous system, as well as endocrine disruption, including effects on thyroid function. The Committee

The enhancing overload caused by fluorides represents a potential factor, having an impact on function of sperm

This is the first time tooth decay has been investigated as a function of individual

osteoid maturation time to increase, suggesting that a toxic effect on osteoblast function or on mineralization had

white matter of spinal cord and the improvement of function after defluoriation. METHODS:  A

in bidistilled Effects of high fluoride and low iodine on thyroid function in offspring

tissues. Fluoride, when in excess, is known to interfere with thyroid gland function. Fluoride-induced thyroid disturbances

vice versa. In an animal study by Guan (1988), fluoride’s effect on thyroid function occurred at lower doses

exceeding the reported short-term exposure levels that impair glucose metabolism and kidney function in human

1969 ). As a goitrogen, doctors believed fluoride could suppress the thyroid’s function and thereby

study of the effect of high fluoride on the function of the

iodine concentration in drinking water on children's dental fluorosis and thyroid function]. Objective: To investigate

Date: July 2000 Volume/Page: 11(4):S153 Type: Human Study , Epidemiology Categories: Brain , Behavior , Cognitive Function , Arsenic , Chemical Co-Exposures

Volume/Page: 40(5):546-54. Type: Animal Study Categories: Brain , Brain Cellular/Tissue Effects , Cognitive Function , Hippocampus , *NTP2019 , Neurotoxicity Abstract

Date: January 2015 Volume/Page: 105(1):72-76. Type: Human Study , Epidemiology Categories: Brain , Cognitive Function , IQ Score , *NTP2019 Download

factors of environmental Effects of excess fluoride and iodide on thyroid function and morphology

Perspectives Publish Date: October 2012 Volume/Page: 120(10):1362-8. Type: Review Categories: Brain , Cognitive Function , IQ Score , Neurotoxicity Download

Blood and urine were monitored for biochemical markers of tissue function, and plasma

also be compromised (given that MT is the main mediator of pineal function). One putative function of

the available information. CONNETT: Is there evidence to suggest that fluoride can affect thyroid function, and if

a two-phase material (hydroxyapatite crystals embedded in a collagen matrix) which can function efficiently only if there

the erosion of enamel in severe fluorosis can impair the function of the

safe for persons with normal kidneys. Systemic fluorosis in patients with diminished renal function, however, seems a

majority of both animal and human research indicates that fluoride can damage cognitive function. Studies Finding an Effect

cases, it increases the risk of harmful effects to dental function; (3) it places dental

Volume/Page: 28(2):254-8. Type: Animal Study Categories: Brain , Brain Cellular/Tissue Effects , Cognitive Function , Chemical Co-Exposures , Hippocampus

Date: October-December 2004. Volume/Page: 37(4):264–270. Type: Animal Study Categories: Brain , Cognitive Function , Susceptible Populations , Chemical Co

Publish Date: June 2011 Volume/Page: 32(6):679-81. Type: Human Study Categories: Brain , Cognitive Function , IQ Score Abstract Objective

study of the effect of high fluoride on the function of the

Fluoride Publish Date: August 1998 Volume/Page: 31(3):S13. Type: Human Study Categories: Brain , Cognitive Function , IQ Score Abstract A

Fluoride Action Network. Publish Date: 1989 Volume/Page: 6:73. Type: Human Study Categories: Brain , Cognitive Function , IQ Score , Endemic fluorosis

and/or As2O3-treated mice in the present study, which could affect brain function. The ingestion

skeletal fluorosis is directly related to the severity of abnormal cardiac function, as demonstrated by the

of serious effects, including arthritis , damage to the developing brain , reduced thyroid function, and possibly

defects in children with [chronic renal failure], since the kidneys have an important function in the

that need the presence of the fluoride ion to function properly. On the

that need the presence of the fluoride ion to function properly. On the

The enhancing overload caused by fluorides represents a potential factor, having an impact on function of sperm

several lines of information indicate an effect of fluoride exposure on thyroid function.” fan newsletter Sign up

that need the presence of the fluoride ion to function properly. On the

be of relevance to fluoride is impairment of thyroid gland function (see Chapter 8). For

to treat severe hip osteoarthritis due to fluorosis, which can significantly improve joint function and has

penetration). According to the authors, such changes “undoubtedly affect the physiological function of the

and as little as 2 years in highly exposed adults with ordinary kidney function. (Roholm 1937; Franke 1975

direction albeit not in degree. . . . Mineralization of this bone . . . was an inverse function of fluoride

ingestion. These hazards include acute toxic hazard, such as to people with  impaired kidney function , as well as chronic

possibility that fluoride ingestion may impair intelligence and other indices of neurological function is supported by a

possibility that fluoride ingestion may impair intelligence and other indices of neurological function is supported by a

Studies : Clinical and biochemical profile of deiodinase enzymes and thyroid function hormones in patients

possibility that fluoride ingestion may impair intelligence and other indices of neurological function is supported by a

influence crystal size, and some evidence indicates that F has an effect on cell function, either directly through interactions

levels in the body by excreting fluoride through the urine. When kidney function declines (due to

of 0.5-2.0 µM (Taves, 1968). Thus it could be speculated that normal function of both

Zakrzewska 2002). The authors noted that these changes “undoubtedly affect the physiological function of the

possibility that fluoride ingestion may impair intelligence and other indices of neurological function is supported by a

cases, it increases the risk of harmful effects to dental function; (3) it places dental

single treatment -- doses that far exceed the doses that can Fluoride Gels & Kidney Function Scientists have found that

and toenails, as well as in our reproduction of her beverage. Renal function was normal. . . . CONCLUSION: Our

to the Mayo Clinic doctors, “s ystemic fluorosis in patients with diminished renal function . . . seems a reasonable

role exists, and that humans do not need fluoride for any physiological function, including the formation

fluoride compounds. It is known that in the presence of insufficient function of the

& IQ: 76 Studies Fluoride & IQ: 76 Studies August 5, 2012 | Jay Sanders Brain Cognitive Function IQ Score Note: See

possibility that fluoride ingestion may impair intelligence and other indices of neurological function is supported by a