publication of clinical trials leads to unrealistic estimates of antidepressant efficacy Selective publication of

Agomelatine ( Valdoxan ) : efficacy and tolerance profile Efficacy and tolerance profile of agomelatine and practical

Unblinding effects may inflate the efficacy of antidepressants in trials using inert placebos Active placebos

in the 5 mg group, 3 in the 100 mg group). Efficacy criteria showed a

as an emotion. Opium was a traditional remedy for melancholic depression; its efficacy is arguably superior to

was independent of the time of drug administration. The efficacy of agomelatine

Sinemet CR in Parkinson's disease Evaluation of equivalent efficacy of sinemet and sinemet

in the relatively immobile 'off' phase. OBJECTIVES: To compare the efficacy and safety

However, BRO is not being studied at present for reasons unrelated to efficacy or side effects. MOC

was independent of the time of drug administration. The efficacy of agomelatine

surfaced that read: "It would be unacceptable to include a statement that efficacy had not been demonstrated

the cholinolytic biperiden as compared to placebo did not enhance the antidepressant efficacy of mianserin

aniracetam may be of benefit, with further trials required to confirm its efficacy profile and to

brief depression Refractory depression Religiosity Resveratrol(?) Retardation Reward Reward/dopamine Reward circuitry Riluzole RIMA RIMAs RIMAs/efficacy Risks Ritanserin (Tisterton) Rivastigmine

surfaced that read: "It would be unacceptable to include a statement that efficacy had not been demonstrated

of such treatment. Paralleling the delay in onset of antidepressant efficacy in humans

35 ABSTRACT T olcapone is a catechol-O-methyltransferase (COMT) inhibitor that has shown efficacy in the

aniracetam may be of benefit, with further trials required to confirm its efficacy profile and to

of such treatment. Paralleling the delay in onset of antidepressant efficacy in humans

the cholinolytic biperiden as compared to placebo did not enhance the antidepressant efficacy of mianserin

as an emotion. Opium was a traditional remedy for melancholic depression; its efficacy is arguably superior to

ongoing neurogenesis. Currently available antipsychotic medications usually fall short of the desired therapeutic efficacy and invariably

as an emotion. Opium was a traditional remedy for melancholic depression; its efficacy is arguably superior to

than placebo in erectile dysfunction of all tested causes. The efficacy of sildenafil

of this study was to gather preliminary data regarding the antidepressant efficacy of agomelatine

the market with the claim of a more favourable tolerability/efficacy profile. OBJECTIVES: The

brief depression Refractory depression Religiosity Resveratrol(?) Retardation Reward Reward/dopamine Reward circuitry Riluzole RIMA RIMAs RIMAs/efficacy Risks Ritanserin (Tisterton) Rivastigmine

Sleep dysfunction and psychiatric illness Agomelatine (Valdoxan) and melatonergic drugs Agomelatine (Valdoxan): efficacy and tolerance

Zopiclone ( Imovane ) Zopiclone. An update of its pharmacology, clinical efficacy and tolerability in the treatment

multicentre, double-blind, between-patient study was carried out to evaluate the efficacy and tolerability

Norset, Remergil ) Review of the results from clinical studies on the efficacy, safety and tolerability

alprazolam a sustained clinical effect. The available investigational clinical trials show good efficacy for this

F 11440 and 5-HT1a F 11440, a potent, selective, high efficacy 5-HT1A receptor agonist with

search for new pharmacologic interventions for smoking cessation. After reviewing the efficacy and safety

Sleep dysfunction and psychiatric illness Agomelatine (Valdoxan) and melatonergic drugs Agomelatine (Valdoxan): efficacy and tolerance

Scopolamine as an anxiolytic antidepressant Antidepressant efficacy of the antimuscarinic drug scopolamine: a randomized, placebo-controlled

5-HT2c Valdoxan Serotonin Melatonin Agomelatine Agomelatine: structure Paroxetine (Paxil, Seroxat) Serotonin 5-HT2C receptors Clinical efficacy of agomelatine

ongoing neurogenesis. Currently available antipsychotic medications usually fall short of the desired therapeutic efficacy and invariably

regulation of 5-HT2C receptors parallels the gradual onset of clinical efficacy of SSRIs

foods may confound results. Finally, large-scale, placebo-controlled, double-blind trials comparing the efficacy and safety

clinically important pharmacokinetic drug-drug interactions. Although no clear relationship exists between the clinical efficacy, plasma concentration of

hearts The antidepressant onion? Folate and unipolar depression Creatine as an antidepressant Antidepressant efficacy of folic

SSRIs and SNRIs SSRIs and SNRIs: broad spectrum of efficacy beyond major depression by Gorman

foods may confound results. Finally, large-scale, placebo-controlled, double-blind trials comparing the efficacy and safety

hearts The antidepressant onion? Folate and unipolar depression Creatine as an antidepressant Antidepressant efficacy of folic

SSRIs and SNRIs SSRIs and SNRIs: broad spectrum of efficacy beyond major depression by Gorman

Sildenafil ( Viagra ) Clinical efficacy of sildenafil citrate based on etiology and response to prior

postsynaptic 5-HT(1A) receptors. The widespread recognition of the clinical efficacy of such

to use an anticonvulsant adjunctively to lithium to assess the efficacy of this

for example, the forced swim test) that are highly predictive of efficacy in humans

application. The mechanism of action of fluoxetine; its metabolism; its efficacy in patients

sex' Prescription Drugs Viagra: mechanisms Phosphodiesterase 5 Sexual pharmacology The Viagra Revolution Viagra: clinical efficacy Semen as an antidepressant

needed to better identify at-risk individuals, to compare the efficacy of various

reuptake inhibitor, clomipramine, paved the way for research into the efficacy of the

and preventing relapse has not been systematically reviewed. OBJECTIVE: To evaluate the efficacy of 5

sex' Prescription Drugs Viagra: mechanisms Phosphodiesterase 5 Sexual pharmacology The Viagra Revolution Viagra: clinical efficacy Semen as an antidepressant

deficiencies in women New antidepressants: agomelatine Agomelatine (Valdoxan) and melatonergic drugs Agomelatine (Valdoxan): efficacy and tolerance

light treatment lowers core temperature during sleep in proportion to its antidepressant efficacy. The regulation

cortisol and mood New antidepressants: agomelatine Agomelatine (Valdoxan) and melatonergic drugs Agomelatine (Valdoxan): efficacy and tolerance

said. Sexsomnia Drugs and sex Designer aphrodisiacs The Viagra Revolution Viagra: clinical efficacy Antidepressants and sex

the HPA axis by antidepressant drugs and clinical reports of antidepressant efficacy with antiglucocorticoid agents. The

Winter depression Melatonin ligands New antidepressants: agomelatine Agomelatine (Valdoxan) and melatonergic drugs Agomelatine (Valdoxan): efficacy and tolerance

whether abstinence rates are maintained with bupropion. In addition, clarification of its efficacy in comparison

SSRIs; citalopram, fluoxetine, fluvoxamine, paroxetine and sertraline) has shown no difference in efficacy between individual compounds but

a mechanism allowing for a marked increase in the efficacy of AD

33(5):642-9 ABSTRACT O BJECTIVE: Controlled trials do not suggest differences in efficacy between antidepressant compounds. Psychiatrists

for severe depression is discussed. METHOD: The relevant literature concerning the efficacy, tolerability and safety

of presynaptic cholinergic function. A few of these compounds have confirmed efficacy in delaying

prostate-specific antigen over control values. Currently, insufficient evidence, primarily regarding psychologic safety and efficacy, exists to warrant

promising to elaborate novel generations of antidepressants that surpass the efficacy and onset

selegiline, bupropion, levodopa, phenylalanine, and tyrosine. Altogether, these studies have demonstrated the efficacy of methylphenidate

pathways. For the 5-HT2A receptor system, all agonists tested had greater relative efficacy for PLA2

severe side effects as compared to conventional benzodiazepines because of their lower efficacy and better

for severe depression is discussed. METHOD: The relevant literature concerning the efficacy, tolerability and safety

and complementary modes of action are more likely to show broad-based efficacy against core and

stress and memory New antidepressants: agomelatine Agomelatine (Valdoxan) and melatonergic drugs Agomelatine (Valdoxan): efficacy and tolerance

Alprazolam ( Xanax , Helix ) Clinical pharmacology, clinical efficacy, and behavioral toxicity of alprazolam: a review of

is available, and further studies are needed to investigate the efficacy of amantadine

ABSTRACT C linical reports suggest that amisulpride, in addition to its antipsychotic efficacy, may also have antidepressant

of presynaptic cholinergic function. A few of these compounds have confirmed efficacy in delaying

in depression and in the mechanism of their therapeutic efficacy. Although it is not

a mechanism allowing for a marked increase in the efficacy of AD

the present randomized, controlled, single-blind study was to evaluate the efficacy and safety

treatment of premenstrual dysphoric disorders. The present study tests the efficacy of L

A n important aim of drug development has been to retain efficacy while reducing side effects

Clinical Excellence (Nice) claimed that "drug companies have successfully withheld important data". Gauging the efficacy of a

Serotonin and the genetics of depression Serotonin reuptake inhibitors v enhancers Antidepressant efficacy and 'publication

Psychiatry 1991 Jul; 148(7):910-6 ABSTRACT O BJECTIVE: This investigation compared the efficacy of the

of the initial phase of therapy. This article examines the relative efficacy of various

inhibitor, has shown potential antidepressant as well as neuroprotective effects. Other MAO inhibitors have shown antidepressant efficacy in animal

double-blind, placebo-controlled parallel-group comparative study was to prove the efficacy and tolerance

Agomelatine The role of melatonin Agomelatine: structure Serotonin 5-HT2C receptors Clinical efficacy of agomelatine

Agomelatine The role of melatonin Agomelatine: structure Serotonin 5-HT2C receptors Clinical efficacy of agomelatine

and the potato: the natural origin of benzodiazepines Pregabalin: its efficacy, safety and tolerability

Melatonin Agomelatine Agomelatine: structure Serotonin 5-HT2c receptors Agomelatine (Valdoxan): review New antidepressants: agomelatine Agomelatine (Valdoxan): efficacy and tolerance

The sedative properties of neuroleptics may contribute to the overall efficacy in the

documents said, "It would be commercially unacceptable to include a statement that efficacy had not been demonstrated

in this area have recently been rewarded by the demonstration of antidepressant efficacy of the

Union and the USA. OBJECTIVES: To determine the clinical efficacy and safety

inhibitors (PDIs) such as carbidopa. Preclinical and clinical evidence for the efficacy of 5