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1-100 of about 169 matches for site:www.fightaging.org site:www.fightaging.org cognitive function
https://www.fightaging.org/archives/2024/05/why-does-oral-microbiome-d...
Why Does Oral Microbiome Diversity Correlate with Late Life Cognitive Function? – Fight Aging! Home FAQ Fund Research Services Investing Therapies Newsletter
https://www.fightaging.org/archives/2024/05/reviewing-the-effects-of-i...
Reviewing the Effects of Intermittent Fasting on Cognitive Function in Later Life – Fight Aging! Home
https://www.fightaging.org/archives/2017/01/towards-a-better-understan...
a Better Understanding of the Effects of Tiny Strokes on Cognitive Decline – Fight Aging! Home
https://www.fightaging.org/archives/2023/10/a-bidirectional-relationsh...
a bidirectional relationship between age-related hearing loss and loss of cognitive function. Their summary is
https://www.fightaging.org/archives/2025/08/chronological-age-doesnt-c...
In today's open access paper, researchers report on correlations between phenotypic age and cognitive function in older
https://www.fightaging.org/archives/2013/08/removing-c1q-in-mice-reduc...
Protein in the CNS during Normal Aging The decline of cognitive function has emerged as
https://www.fightaging.org/archives/2023/10/more-evidence-for-impaired...
have to be evaluated. Immediate and delayed recall as measures of cognitive function were assessed in
https://www.fightaging.org/archives/2023/01/evidence-for-age-related-h...
include (i) common underlying pathology (probably vascular), (ii) impoverished input affecting brain structure and function, (iii) cognitive resources overoccupied
https://www.fightaging.org/archives/2024/06/fight-aging-newsletter-jun...
an Approach to Slow Aging Why Does Oral Microbiome Diversity Correlate with Late Life Cognitive Function? Reviewing the
https://www.fightaging.org/archives/2008/12/a-novel-view-of-inflammagi...
ultimately have negative impacts on metabolism, bone density, strength, exercise tolerance, the vascular system, cognitive function, and mood
https://www.fightaging.org/archives/2008/08/biomarkers-of-aging-at-sag...
a batch of different kinds of changes. Changes in kidney function, liver function, cognitive function
https://www.fightaging.org/archives/2014/05/gdf11-reverses-some-aspect...
somewhat reversing a number of measures of aging. Stem cell function declines with age in
https://www.fightaging.org/archives/2025/08/mesenchymal-progenitor-cel...
transcriptomic , and methylomic -consistently indicated biological age reversal. Notably, SRC-treated monkeys exhibited improved cognitive function, restored cortical architecture
https://www.fightaging.org/archives/2016/03/evidence-for-fkbp1b-declin...
old rats and observed resulting improvements in specific measures of cognitive function: Brain Ca2+ regulatory
https://www.fightaging.org/archives/2022/11/what-is-the-relationship-b...
account for a meaningful fraction of the loss of cognitive function and related
https://www.fightaging.org/archives/2024/05/
to help » May 31st, 2024 Reviewing the Effects of Intermittent Fasting on Cognitive Function in Later
https://www.fightaging.org/archives/2024/05/less-soluble-klotho-greate...
Circulating α-klotho appears to have effects on the brain, however, improving cognitive function even in
https://www.fightaging.org/archives/2014/10/dementia-as-a-consequence-...
on the aging brain that affects a different range of cognitive function and contributes
https://www.fightaging.org/rejuvenation-therapies/
of Alzheimer's patients, there was little to no observed benefit to cognitive function or pace of
https://www.fightaging.org/archives/2016/06/a-short-list-of-potential-...
with aging, and again, removing it improves the state of cognitive function in later
https://www.fightaging.org/archives/2025/08/fight-aging-newsletter-aug...
In today's open access paper, researchers report on correlations between phenotypic age and cognitive function in older
https://www.fightaging.org/archives/2025/03/fight-aging-newsletter-mar...
US Detrimental Changes in the Gut Microbiome Correlate with Loss of Cognitive Function in Later
https://www.fightaging.org/archives/2025/03/
of cerebrospinal fluid drainage as an important contribution to loss of cognitive function and the
https://www.fightaging.org/archives/2024/05/microglia-become-progressi...
be an important contribution to neurodegenerative conditions and loss of cognitive function more generally. Researchers
https://www.fightaging.org/archives/2022/08/
microbiome and neural function. Although the gut microbiome has been associated with cognitive function, it remains to
https://www.fightaging.org/archives/2023/11/frailty-correlates-with-he...
difficulty with communication and hinders spatial awareness . This may eventually lead to cognitive and physical
https://www.fightaging.org/archives/2024/07/fight-aging-newsletter-jul...
the brain, TAC alleviates neuroinflammation, increases neurotrophic factors, stimulates adult neurogenesis, and preserves cognitive function without evident toxicity
https://www.fightaging.org/archives/2015/08/a-review-of-the-state-of-h...
present in young or aged blood are sufficient to improve or impair cognitive function, respectively, suggesting an
https://www.fightaging.org/archives/2016/09/a-visual-introduction-to-s...
disease , and also (more slowly) in everyone else's, and impairs cognitive function. There are also
https://www.fightaging.org/
mutations . The only exceptions are interventions that act to improve the function of the
https://www.fightaging.org/archives/2024/07/fight-aging-newsletter-jul...
in the Greenland Shark Chronic Inflammation in Early Adulthood Correlates with Worse Cognitive Function in Middle
https://www.fightaging.org/archives/2025/05/fight-aging-newsletter-may...
life/ This very interesting paper finds evidence of early adult impairment of cognitive function to correlate
https://www.fightaging.org/archives/2025/02/fight-aging-newsletter-feb...
Secretion in Aging Nicotinamide Riboside Fails to Improve Measures of Cognitive Function in Mild
https://www.fightaging.org/archives/2015/07/more-on-beta-2-microglobul...
target this protein therapeutically." β2-microglobulin is a systemic pro-aging factor that impairs cognitive function and neurogenesis
https://www.fightaging.org/archives/2024/06/why-does-hypertension-corr...
number of other aspects of aging, such as frailty , Alzheimer's disease , cognitive decline , and microstructural
https://www.fightaging.org/archives/2025/03/fight-aging-newsletter-mar...
org/services/ Contents Partial Depletion of Microglia in the Brain Improves Cognitive Function in Aged
https://www.fightaging.org/archives/2023/12/building-aging-clocks-for-...
Some recent methods have used clinical chemistry markers which include some markers of organ function. However, many of
https://www.fightaging.org/archives/2025/05/
to the hippocampus with Aβ oligomer injection, aged mice suffered sustained deficits, including impaired cognitive function, further reduced neurogenesis
https://www.fightaging.org/archives/2025/04/fight-aging-newsletter-apr...
of cerebrospinal fluid drainage as an important contribution to loss of cognitive function and the
https://www.fightaging.org/archives/2025/08/hypertension-allows-harmfu...
to tissues throughout the body. Pressure damage directly damages tissue structure, disrupts tissue function, and alters
https://www.fightaging.org/archives/2023/12/
to neuroinflammation. Delving into the development of therapies, measures of cognitive function have been improved
https://www.fightaging.org/archives/2025/07/accelerated-biological-age...
age (PhenoAge) - and a new comorbidity model encompassing physical, psychological, and cognitive disorders, with overall mortality
https://www.fightaging.org/archives/2021/05/
advancement of therapeutic strategies to protect synaptic activity and subsequent cognitive function. Here, we review
https://www.fightaging.org/archives/2022/01/
way to reduce the impact of neurodegeneration and improve cognitive function. It is one
https://www.fightaging.org/archives/2022/12/
of regenerative capacity in the heart; cardiovascular disease in general; cognitive function and brain
https://www.fightaging.org/archives/2020/10/
Senolytic Prodrug is Demonstrated to Reverse Frailty and Loss of Cognitive Function in Old
https://www.fightaging.org/archives/2023/08/
of people with Alzheimer's experience these issues, including difficulty sleeping and worsening cognitive function at night. However
https://www.fightaging.org/archives/2023/11/
the quality of an intervention in each of muscle function, cognitive function, and
https://www.fightaging.org/archives/2025/03/fight-aging-newsletter-mar...
by the FDA. They caused only a small improvement in cognitive function, probably because they
https://www.fightaging.org/archives/2025/04/fight-aging-newsletter-apr...
Exposure to Air Pollution Increases Frailty Risk Particular Air Pollution Exposure Correlates with Worse Cognitive Function Transfer RNA May
https://www.fightaging.org/archives/2024/10/fight-aging-newsletter-oct...
Forcing these cells back into action may produce a beneficial improvement in cognitive function. CRISPR-Cas9 screens
https://www.fightaging.org/archives/2021/07/
of the DLPFC and its neuronal networks could improve the cognitive function and motor
https://www.fightaging.org/archives/2020/01/
for loss of volume to correlate with loss of cognitive function. It is unclear
https://www.fightaging.org/archives/2024/12/fight-aging-newsletter-dec...
observed in regions susceptible to neurodegeneration and important for cognitive function. Studies have also
https://www.fightaging.org/archives/2023/11/age-related-hearing-loss-c...
microstructural changes in the brain indicative of loss of function. Evidence from studies involving
https://www.fightaging.org/archives/2024/02/fight-aging-newsletter-feb...
the connection between the WWI and three tests of low cognitive function in US
https://www.fightaging.org/archives/2020/09/
and longevity in old age. Older people have become younger: physical and cognitive function have improved meaningfully
https://www.fightaging.org/archives/2024/07/fight-aging-newsletter-jul...
an early contributing cause of neurodegenerative conditions and loss of cognitive function. There is a
https://www.fightaging.org/archives/2021/03/
resistance , endothelial dysfunction , body fat, genomic toxicity , muscle strength, gait speed , exercise capacity, and cognitive function. The benefits
https://www.fightaging.org/archives/2024/07/
responses, the circadian rhythm , and microbial metabolites, by which gut microbiomes influence cognitive function by impacting CNS
https://www.fightaging.org/archives/2024/04/
between cardiometabolic multimorbidity and changes in global and domain-specific cognitive function and (2
https://www.fightaging.org/archives/2025/01/
across the body, regulating metabolic processes, reducing inflammation, supporting tissue repair, and maintaining cognitive function. The release
https://www.fightaging.org/archives/2020/05/
protective factor for brain health, the mechanisms by which physical activity affect cognitive function are not fully
https://www.fightaging.org/archives/2024/06/fight-aging-newsletter-jun...
the only significant benefit occurred in an owner-reported measure of cognitive function. There was no
https://www.fightaging.org/archives/2025/08/
of concept demonstration in mouse models of neurodegenerative disease , showing improved cognitive function following treatment. In
https://www.fightaging.org/archives/2024/05/fight-aging-newsletter-may...
microglia-to-a-more-youthful-phenotype/ Exercise is known to improve cognitive function and neurogenesis
https://www.fightaging.org/archives/2024/11/
and psychological mechanisms. Physiologically, sports confer efficiency advantages in information processing and cognitive function by increasing cerebral
https://www.fightaging.org/archives/2025/07/fight-aging-newsletter-jul...
lipopolysaccharides at 0.5 mg/kg for 7 consecutive days. To evaluate cognitive function, C57BL/6J mice
https://www.fightaging.org/archives/2025/08/potential-therapeutic-appr...
of scans in hypertensive patients who had a stroke or exhibit cognitive dysfunction and for
https://www.fightaging.org/archives/2024/03/fight-aging-newsletter-mar...
gut microbiome via dietary supplementation with a prebiotic produced modest benefits to cognitive function. It is interesting
https://www.fightaging.org/archives/2025/01/fight-aging-newsletter-jan...
we previously found no beneficial effects of microglial repopulation on either amyloid pathology nor cognitive function in aged
https://www.fightaging.org/archives/2024/05/fight-aging-newsletter-may...
be an important contribution to neurodegenerative conditions and loss of cognitive function more generally. Researchers
https://www.fightaging.org/archives/2020/11/
mitochondrial functionality. These effects were associated with decreased inflammation and reduced tissue atrophy, improved cognitive function, and diminished
https://www.fightaging.org/archives/2024/12/
reducing hypertension. Or in the brain , where it reverses loss of cognitive function and is
https://www.fightaging.org/archives/2020/12/
in the brain . Transplanting gut microbes from old mice to young mice impairs cognitive function . When it comes
https://www.fightaging.org/archives/2024/03/fight-aging-newsletter-mar...
and natural aging mice. The intravenous injection of USC-EVs improves cognitive function, increases physical fitness
https://www.fightaging.org/archives/2024/04/fight-aging-newsletter-apr...
more than 40% of the world's population and impacting patients' cognitive function. Although the
https://www.fightaging.org/archives/2024/06/
as the outcome, as evaluated by self-reported chronic conditions, physical and cognitive function, and mental
https://www.fightaging.org/archives/2025/05/fight-aging-newsletter-may...
competitors to assess before and after functional assays of immune function, cognitive capacity, and
https://www.fightaging.org/archives/2024/01/
during early development and continues to influence learning, memory, and cognitive function throughout life. Recent
https://www.fightaging.org/archives/2024/03/
multiple sclerosis , but age-related loss of myelination does appear to degrade cognitive function. Researchers are thus
https://www.fightaging.org/archives/2017/12/useful-tests-for-self-expe...
are incorporated in brain phospholipid mitochondrial membrane's fatty acid composition (omega-3 improve cognitive function and reduce
https://www.fightaging.org/archives/2024/11/fight-aging-newsletter-nov...
the blood stream. That the increased blood flow that occurs following exercise improves cognitive function in the
https://www.fightaging.org/archives/2025/04/fight-aging-newsletter-apr...
Again, an impaired drainage of cerebrospinal fluid correlates with worse loss of cognitive function and progression
https://www.fightaging.org/archives/2021/10/
notably in the hippocampus, which is critical to memory and cognitive function." Researchers used a
https://www.fightaging.org/archives/2025/08/antiviral-treatment-fails-...
included 120 adults, age 71 on average, all diagnosed with early Alzheimer's disease or mild cognitive impairment with imaging or
https://www.fightaging.org/archives/2024/08/fight-aging-newsletter-aug...
responses, the circadian rhythm, and microbial metabolites, by which gut microbiomes influence cognitive function by impacting CNS
https://www.fightaging.org/archives/2025/03/fight-aging-newsletter-mar...
of Dasatinib and Quercetin improved aspects of both physical and cognitive function in mice
https://www.fightaging.org/archives/2024/05/fight-aging-newsletter-may...
between cardiometabolic multimorbidity and changes in global and domain-specific cognitive function and (2
https://www.fightaging.org/archives/2025/06/fight-aging-newsletter-jun...
into their 60s without developing a chronic disease or sizable loss of cognitive function is 30% to
https://www.fightaging.org/archives/2025/04/fight-aging-newsletter-apr...
the most common form of dementia, characterized by an irreversible decline in cognitive function. The pathogenesis
https://www.fightaging.org/archives/2022/06/
can interfere in the signaling between neurons that is necessary for cognitive function. Interestingly, they also
https://www.fightaging.org/archives/2025/06/fight-aging-newsletter-jun...
klotho has minimal side-effects, and is wholly beneficial for at least cognitive function and kidney
https://www.fightaging.org/archives/2024/12/fight-aging-newsletter-dec...
in later stages of Alzheimer's disease as cells die and cognitive function is lost. So
https://www.fightaging.org/archives/2024/12/fight-aging-newsletter-dec...
delivery of PF4 can dampen neuroinflammation in old animals and restore cognitive function. PF4 doesn't
https://www.fightaging.org/archives/2024/08/fight-aging-newsletter-aug...
Be Advantageous An Epigenetic Clock Using Retrotransposon DNA Methylation The Second X Chromosome Slows Cognitive Aging Treatments for
https://www.fightaging.org/archives/2025/01/fight-aging-newsletter-jan...
question is whether IF can be integrated into existing lifestyle recommendations to further support cognitive function in the
https://www.fightaging.org/archives/2025/02/fight-aging-newsletter-feb...
population, and is thought to provide some contribution to declining cognitive function and conditions
https://www.fightaging.org/archives/2025/01/fight-aging-newsletter-jan...
reducing hypertension. Or in the brain, where it reverses loss of cognitive function and is
https://www.fightaging.org/archives/2024/10/fight-aging-newsletter-oct...
Microbiome in Aging Investigating the Age-Related Decline of Choroid Plexus Function Senescent Microglia are Likely