limited number of folds ( Figure 30.2 ). Among them, there is a strong predominance of β

Fever in adults and pediatric patients 3 months or older Intravenous ibuprofen lysine:   Patent ductus arteriosus (PDA

of POFUT1 in Drosophila or mice results in embryonic lethality with strong Notch developmental defects, indicating

lysosomes in normal cells. Because the high-uptake property was destroyed by strong periodate treatment, which oxidizes

A chain may not be an efficient substrate for ubiquitination because it has few lysine residues. FIGURE 31.4

the GlcNAc-phosphotransferase involved in lysosomal enzyme targeting (see Chapter 23 ) recognizes specific lysine residues and other

underlying glycan. Neither hCD22 nor mCD22 binds 9-O-acetylated Sias; mCD22 has a strong preference for Neu5Gc

an immune response on its own, when it is coupled covalently to a lysine side chain on a

infections, and an asymptomatic carrier state) ( Fig. 1 ). Particular serovars show a strong propensity to produce

arterial disease, nicotine and cigarette smoke decrease CBF. Cigarette smoking is a strong risk factor for