1-100 of about 200 matches for site:www.thno.org site:www.thno.org bioactive
Enhanced osseointegration of three-dimensional supramolecular bioactive interface through osteoporot
https://www.thno.org/v10p4779.htm
Enhanced osseointegration of three-dimensional supramolecular bioactive interface through osteoporotic microenvironment regulation Theranostics 13.3 Impact Factor Home Aims
Bioactive antibacterial silica-based nanocomposites hydrogel scaffolds with high angiogenesis for pr
https://www.thno.org/v10p4929.htm
Theranostics 2020; 10(11):4929-4943. doi:10.7150/thno.41839 This issue Cite Research Paper Bioactive antibacterial silica-based nanocomposites
https://www.thno.org/v10p4720.htm
Theranostics 2020; 10(11):4720-4736. doi:10.7150/thno.43092 This issue Cite Research Paper Bioactive phospho-therapy with black
Aligned chitosan nanofiber hydrogel grafted with peptides mimicking bioactive brain-derived neurotro
https://www.thno.org/v10p1590.htm
Aligned chitosan nanofiber hydrogel grafted with peptides mimicking bioactive brain-derived neurotrophic factor and vascular endothelial growth factor repair
Engineering Bioactive Self-Healing Antibacterial Exosomes Hydrogel for Promoting Chronic Diabetic Wo
https://www.thno.org/v09p0065.htm
Engineering Bioactive Self-Healing Antibacterial Exosomes Hydrogel for Promoting Chronic Diabetic Wound Healing and Complete
GPX1-driven selenium nanoplatform reprograms MAMs-mediated organelle crosstalk to reverse inflammato
https://www.thno.org/v15p9601.htm
of SeNPs [ 40 , 41 ]. Moreover, previous studies have reported that LNT, as a natural bioactive polysaccharide, possesses excellent biocompatibility
Alisol A ameliorates vascular cognitive impairment via AMPK/NAMPT/SIRT1-mediated regulation of chole
https://www.thno.org/v15p9415.htm
centuries. The herbs included in this formula are rich in bioactive compounds with known metabolic
https://www.thno.org/v10i11
10(11): 4900-4902. doi:10.7150/thno.44568 Full text PDF PubMed PMC Research Papers Bioactive phospho-therapy with black
https://www.thno.org/v16i2
2): 830-851. doi:10.7150/thno.112836 Full text PDF Sequential release of bioactive factors from functionalized metal
https://www.thno.org/v15i2
459. doi:10.7150/thno.102626 Full text PDF PubMed PMC Advancements in GelMA bioactive hydrogels: Strategies for
https://www.thno.org/v16p0398.htm
preventing cellular necrosis and facilitating functional recovery [ 23 , 24 ]. Recent studies have shown that bioactive metal ions such as
Biofilm-disrupting heterojunction microneedles: dual ROS amplification and glucose deprivation for a
https://www.thno.org/v15p9757.htm
while the tip layer would puncture the skin and deliver bioactive nanomaterials for treatment
https://www.thno.org/v12i10
12(10): 4779-4790. doi:10.7150/thno.72339 Abstract Full text PDF PubMed PMC Errata Bioactive antibacterial silica-based nanocomposites
https://www.thno.org/v12i11
5237-5257. doi:10.7150/thno.70884 Full text PDF PubMed PMC Reviews Extracellular vesicles as bioactive nanotherapeutics: An emerging paradigm
https://www.thno.org/v11i17
for the prevention of heart failure by inhalation of intrinsically bioactive nanoparticles Chao Liu, Liyuan
https://www.thno.org/v15i14
Theranostics 2025; 15(14): 6857-6881. doi:10.7150/thno.112782 Full text PDF PubMed PMC Bioactive metal-protein matrix for
https://www.thno.org/v15i5
5): 1715-1740. doi:10.7150/thno.106597 Full text PDF PubMed PMC Stimulus-responsive smart bioactive glass composites for
https://www.thno.org/v10i14
Theranostics 2020; 10(14): 6530-6543. doi:10.7150/thno.44417 Full text PDF PubMed PMC Bioactive poly (methyl methacrylate) bone
https://www.thno.org/v10i4
7150/thno.40103 Full text PDF PubMed PMC Aligned chitosan nanofiber hydrogel grafted with peptides mimicking bioactive brain-derived neurotrophic factor
https://www.thno.org/v11p1129
Life Sciences, State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Bioactive Materials of Ministry
https://www.thno.org/v13p5207
functionalized with acetyl-CoA binding protein (ACBP) to capture acetyl-CoA using an injectable bioactive nanoparticle ( siFoxM1 -ACBP-NP
A skeleton muscle model using GelMA-based cell-aligned bioink processed with an electric-field assis
https://www.thno.org/v11p0048
biomedical substitutes used in muscle tissue regeneration are appropriate topographical cues and bioactive components for the
Zwitterionic rhodamine-CPT prodrug nanoparticles with GSH/H2O2 responsiveness for cancer theranostic
https://www.thno.org/v13p0267
for better identification of cancerous lesions, achieve rapid internalization into cancer cells, selectively release bioactive CPT as a
https://www.thno.org/v12p4051
and human placental extracts (hPE) embedded in the scaffold were used as bioactive components. Methods: Various cell
https://www.thno.org/v12p4051.htm
and human placental extracts (hPE) embedded in the scaffold were used as bioactive components. Methods: Various cell
A 9-kDa matricellular SPARC fragment released by cathepsin D exhibits pro-tumor activity in the trip
https://www.thno.org/v11p6173.htm
the tumor microenvironment through limited SPARC proteolysis, revealing a novel targetable 9-kDa bioactive SPARC fragment for
Hydroxyurea ameliorates atherosclerosis in ApoE-/- mice by potentially modulating Niemann-Pick C1-li
https://www.thno.org/v12p7775
Hospital of Jilin University, Changchun, 130021, China. 2. State Key Laboratory of Bioactive Substance and Function
Supramolecular nanofibers co-loaded with dabrafenib and doxorubicin for targeted and synergistic the
https://www.thno.org/v13p2140
of Medicinal Chemical Biology, College of Life Sciences, Key Laboratory of Bioactive Materials, Ministry of
https://www.thno.org/v12p1132
of Medicinal Chemical Biology, Nankai University, Tianjin 300350, China. 2. Key Laboratory of Bioactive Materials for the
Encapsulation of LXR ligand by D-Nap-GFFY hydrogel enhances anti-tumorigenic actions of LXR and remo
https://www.thno.org/v11p2634
Life Sciences, State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Bioactive Materials of Ministry
Extracellular vesicles from apoptotic BMSCs ameliorate osteoporosis via transporting regenerative si
https://www.thno.org/v14p3583.htm
rRNA, miRNA, or fragments of these RNA molecules) [ 12 - 14 ], thereby acting as new bioactive carriers in balancing
Neural-enhancing PRP/Alg/GelMA triple-network hydrogel for neurogenesis and angiogenesis after spina
https://www.thno.org/v15p3837.htm
characterization of neural regeneration-enhanced triple-network hydrogel The use of bioactive hydrogels for in
https://www.thno.org/v11i20
Theranostics 2021; 11(20): 10173. doi:10.7150/thno.68367 Full text PDF PubMed PMC Engineering Bioactive Self-Healing Antibacterial Exosomes
https://www.thno.org/v8i7
Theranostics 2018; 8(7): 1923-1939. doi:10.7150/thno.22834 Full text PDF PubMed PMC Bioactive Scaffolds for Regeneration
https://www.thno.org/v9i1
2019; 9(1): 48-64. doi:10.7150/thno.29715 Full text PDF PubMed PMC Engineering Bioactive Self-Healing Antibacterial Exosomes
https://www.thno.org/v9i21
9(21): 6284-6299. doi:10.7150/thno.35892 Full text PDF PubMed PMC Copper-incorporated bioactive glass-ceramics inducing anti
An intestinal model with a finger-like villus structure fabricated using a bioprinting process and c
https://www.thno.org/v10p2495.htm
growth factor, and so on [ 17 , 18 ]. Owing to the various bioactive components of the
Therapeutic potential of garlic chive-derived vesicle-like nanoparticles in NLRP3 inflammasome-media
https://www.thno.org/v11p9311.htm
lipids, and RNAs. Growing evidence indicates that dietary VLNs are stable, bioavailable, and bioactive in consumers
https://www.thno.org/v03p0003.htm
niches, includes i) α-chemokine CXCL12 (stromal derived factor-1; SDF-1) [ 4 , 8 - 10 ], ii) bioactive lipids, such as sphingosine
Human pluripotent stem cell-derived ectomesenchymal stromal cells promote more robust functional rec
https://www.thno.org/v12p0143.htm
in the host animals [ 13 - 15 ]. Cumulatively, these studies strongly suggest that MSCs secrete bioactive factors that promote endogenous
Acceleration of chronic wound healing by bio-inorganic polyphosphate: In vitro studies and first cli
https://www.thno.org/v12p0018.htm
assay. The fabricated polyP-supplemented collagen mats were not only biocompatible and bioactive for HUVEC
Human amniotic mesenchymal stromal cells promote bone regeneration via activating endogenous regener
https://www.thno.org/v10p6216.htm
arrays, and found significant differences in the expressions of 23 bioactive factors (Figure 1 B
Active microneedle patch equipped with spontaneous bubble generation for enhanced rheumatoid arthrit
https://www.thno.org/v15p3424.htm
of Pharmaceutical Sciences, Hainan University, Haikou 570200, China. 3. State Key Laboratory of Bioactive Molecules and Druggability
Exosomes of human adipose stem cells mitigate irradiation injury to salivary glands by inhibiting ep
https://www.thno.org/v15p1622.htm
damage are still not fully understood. Exosomes (Exo) are crucial for intercellular communication, transferring bioactive molecules (such as microRNAs
https://www.thno.org/v15p2185.htm
characterization of GtnSH/GtnMI/MgO 2 bioinks Gelatin is biocompatible, biodegradable, and bioactive, making it the
Zwitterionic rhodamine-CPT prodrug nanoparticles with GSH/H2O2 responsiveness for cancer theranostic
https://www.thno.org/v13p0267.htm
for better identification of cancerous lesions, achieve rapid internalization into cancer cells, selectively release bioactive CPT as a
https://www.thno.org/v02p0481.htm
of peptides with different radionuclides. Several clinically relevant radionuclides have been used for labeling bioactive peptides either for
Multiple mitochondria-targeted components screened from Sini decoction improved cardiac energetics a
https://www.thno.org/v13p0510.htm
as a stationary phase, provides a powerful tool for screening bioactive compounds from complex matrices
Bi-directional regulation functions of lanthanum-substituted layered double hydroxide nanohybrid sca
https://www.thno.org/v11p6717.htm
La), a member of REEs family, is used as a bioactive element for bone
https://www.thno.org/v12p5404.htm
cytokines, and peptides [ 10 - 12 ]. In the scaffold-based approach, various bioactive materials and designs
https://www.thno.org/v11p1129.htm
Life Sciences, State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Bioactive Materials of Ministry
https://www.thno.org/v01p0102.htm
and noninvasive modality for visualization, localization, and measurement of bioactive molecules, molecular recognitions, and
Micro/nano-bubble-assisted ultrasound to enhance the EPR effect and potential theranostic applicatio
https://www.thno.org/v10p0462.htm
a higher resistance to water permeation than to air [ 92 , 93 ]. Recently, bioactive gases that have significant
https://www.thno.org/v13p3707.htm
option Reference Manager (RIS). Click on Import. File import instruction Abstract Background: Extracellular vesicles (EVs) carry bioactive molecules associated with various
Fibroblast activation protein α activatable theranostic pro-photosensitizer for accurate tumor imagi
https://www.thno.org/v12p3610.htm
possessed favorable blood stability when incubation with serum. Nevertheless, FAP-MB-8 was readily cleaved by bioactive substance and released
https://www.thno.org/v13p2811.htm
773 2. Li R, Liu K, Huang X, Li D, Ding J, Liu B. et al . Bioactive materials promote wound healing
https://www.thno.org/v12p5675.htm
in the lipid phosphate phosphatase family (LPP1-3) that dephosphorylate extracellular and intracellular bioactive lipid phosphates and
Discovery of 2-deoxy glucose surfaced mixed layer dendrimer: a smart neuron targeted systemic drug d
https://www.thno.org/v14p3221.htm
The availability of non-invasive drug delivery systems capable of efficiently transporting bioactive molecules across the
Modulating the cobalt dose range to manipulate multisystem cooperation in bone environment: a strate
https://www.thno.org/v10p1074.htm
20 , 21 ]. The release of cobalt ions from the cobalt bioactive glass/collagen-glycosaminoglycan composites
Oxygen carrier in core-shell fibers synthesized by coaxial electrospinning enhances Schwann cell sur
https://www.thno.org/v10p8957.htm
study, we explored coaxial electrospinning for its ability to encapsulate water-soluble bioactive agents into core-shell
Tumor-responsive cuproptosis nanoinducer realizing efficient PANoptosis for enhanced cancer immunoth
https://www.thno.org/v15p9294.htm
Rao 4, , Yong Cui 2, , Zhaohui Wang 1,3, 1. State Key Laboratory of Bioactive Substance and Function
https://www.thno.org/v02p0148.htm
A, Yuan H, Reynolds F, Weissleder R. et al . Fate of a bioactive fluorescent wortmannin derivative in
A bioceramic scaffold composed of strontium-doped three-dimensional hydroxyapatite whiskers for enha
https://www.thno.org/v10p1572.htm
is expected [ 4 , 9 ]. To further improve the mechanical and bioactive capacities, our group previously
https://www.thno.org/v10p3533.htm
materials, properties, such as surface properties, particle size, porosity, and release of bioactive ions, are the
A general-purpose Nanohybrid fabricated by Polymeric Au(I)-peptide precursor to wake the function of
https://www.thno.org/v10p8513.htm
pharmaceutical obstacles. Up to know, the rational design of ideally bioactive, stable and bioavailable
Proinflammatory macrophage-derived microvesicles exhibit tumor tropism dependent on CCL2/CCR2 signal
https://www.thno.org/v10p6581.htm
tropism, and are capable of overcoming complex biological barriers to shuttle bioactive cargoes [ 3 ]. On the
A natural small molecule isoginkgetin alleviates hypercholesterolemia and atherosclerosis by targeti
https://www.thno.org/v15p4325.htm
in rats with metabolic dysfunction-associated steatotic liver disease (MASLD), though the specific bioactive components and target
Inhibition of CAV1 attenuates diabetic cardiomyopathy through reducing ferroptosis via activating NR
https://www.thno.org/v15p4989.htm
Affiliated Hospital of Shihezi University, Shihezi, 832003, China. 10. Key Laboratory of Bioactive Materials, Ministry of
A novel pathway for stemness propagation and chemoresistance in non-small cell lung cancer via phosp
https://www.thno.org/v15p3439.htm
tumor progression [ 21 ]. While sEVs are recognized for their role in transferring bioactive molecules that contribute to
Biomimetic piezoelectric hydrogel system for energy metabolism reprogramming in spinal cord injury r
https://www.thno.org/v15p4955.htm
26. Li C, Zhang S, Yao Y, Wang Y, Xiao C, Yang B. et al . Piezoelectric Bioactive Glasses Composite Promotes Angiogenesis
Monovalent antibody-conjugated lipid-polymer nanohybrids for active targeting to desmoglein 3 of ker
https://www.thno.org/v11p4567.htm
and monovalent antibody treatments maintained keratinocyte aggregation ( Figure S3 ). Therefore, the antibody is not bioactive and is
https://www.thno.org/v11p2594.htm
by caspases to avoid alerting the immune system [ 11 , 12 ]. Full length bioactive IL-33 is released
Labeling Human Mesenchymal Stem Cells with Gold Nanocages for in vitro and in vivo Tracking by Two-P
https://www.thno.org/v03p0532.htm
reaction ( Figure 1 A ). Due to their capability to carry bioactive substances within the
Encapsulation of LXR ligand by D-Nap-GFFY hydrogel enhances anti-tumorigenic actions of LXR and remo
https://www.thno.org/v11p2634.htm
Life Sciences, State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Bioactive Materials of Ministry
https://www.thno.org/v01p0058.htm
on the outer surface of cell membranes (extracellular). All these factors make small bioactive peptides excellent candidates for
https://www.thno.org/v09p7807.htm
of the versatility and diversity of peptide-based materials with distinct bioactive properties and discuss
https://www.thno.org/v12p1132.htm
of Medicinal Chemical Biology, Nankai University, Tianjin 300350, China. 2. Key Laboratory of Bioactive Materials for the
https://www.thno.org/v13p5207.htm
functionalized with acetyl-CoA binding protein (ACBP) to capture acetyl-CoA using an injectable bioactive nanoparticle ( siFoxM1 -ACBP-NP
A skeleton muscle model using GelMA-based cell-aligned bioink processed with an electric-field assis
https://www.thno.org/v11p0048.htm
biomedical substitutes used in muscle tissue regeneration are appropriate topographical cues and bioactive components for the
https://www.thno.org/v02p0271.htm
48 :1180-1189 44. Pantarotto D, Briand JP, Prato M. et al . Translocation of bioactive peptides across cell membranes
Integrin β3-PKM2 pathway-mediated aerobic glycolysis contributes to mechanical ventilation-induced p
https://www.thno.org/v12p6057.htm
Zagorodnyaya EB, Oskol'skii GI, Basharov AY, Lushnikova EL, Nepomnyashchikh LM, Zagorodnii AS. Biopolymeric film containing bioactive naphthoquinone (shikonin) in
Exosomes derived from CD271+CD56+ bone marrow mesenchymal stem cell subpopoulation identified by sin
https://www.thno.org/v14p0510.htm
therapeutic effects of MSCs are mediated by the secretion of bioactive components, including cytokines, growth
https://www.thno.org/v13p1843.htm
through the sulfur-conversion pathway, followed by selenoprotein biosynthesis [ 43 ]. Selenocysteine is the bioactive center of selenoprotein
Proteomic analysis reveals ginsenoside Rb1 attenuates myocardial ischemia/reperfusion injury through
https://www.thno.org/v11p1703.htm
transitions of complex I in ischemic injury. Ginsenosides, the main bioactive components in Panax
https://www.thno.org/v02p0723.htm
doi:10.1056/NEJM199903113401004 6. Maherani B, Arab-Tehrany E, Linder M. Mechanism of Bioactive Transfer through Liposomal Bilayers
Superparamagnetic Iron Oxide Nanoparticles as MRI contrast agents for Non-invasive Stem Cell Labelin
https://www.thno.org/v03p0595.htm
aqueous phase using a library of PEG derivatives followed by functionalization with bioactive molecules for cellular
Fibroblast-derived extracellular vesicles as trackable efficient transporters of an experimental nan
https://www.thno.org/v14p0176.htm
action of mKate2 100K-EVs EVs contain a variety of bioactive molecules, including proteins and
https://www.thno.org/v11p9217.htm
effects in the TME. On the other hand, Trp degradation produces bioactive downstream metabolites. These metabolites
Supramolecular nanofibers co-loaded with dabrafenib and doxorubicin for targeted and synergistic the
https://www.thno.org/v13p2140.htm
of Medicinal Chemical Biology, College of Life Sciences, Key Laboratory of Bioactive Materials, Ministry of
1α,25(OH)2D3 ameliorates insulin resistance by alleviating γδ T cell inflammation via enhancing fruc
https://www.thno.org/v13p5290.htm
of type 2 diabetes (T2D) [ 1 - 4 ]. Previous studies have shown that vitamin D (its bioactive form 1α,25(OH
Hydroxyurea ameliorates atherosclerosis in ApoE-/- mice by potentially modulating Niemann-Pick C1-li
https://www.thno.org/v12p7775.htm
Hospital of Jilin University, Changchun, 130021, China. 2. State Key Laboratory of Bioactive Substance and Function
https://www.thno.org/v13p0472.htm
were treated with TBAF, and then deprotected to obtain 17 - 18 , two bioactive phosphate analogs ( Scheme S5
https://www.thno.org/v03p0047.htm
for the three key substituents. Moreover, indoles represent an important class of bioactive compounds whose properties are
LINC00982-encoded protein PRDM16-DT regulates CHEK2 splicing to suppress colorectal cancer metastasi
https://www.thno.org/v14p3317.htm
Laboratory of Tumor Molecular Biology and State Key Laboratory of Bioactive Molecules and Druggability
https://www.thno.org/v13p3675.htm
holes in the skin to directly and evenly deliver bioactive ZnMOF particles to
Xeno-free cultured mesenchymal stromal cells release extracellular vesicles with a “therapeutic” miR
https://www.thno.org/v13p1470.htm
induce cells to perform the most suitable therapeutic response by EV-encapsulated bioactive factors. Methods: A
Recent advances and challenges in hydrogel-based delivery of immunomodulatory strategies for diabeti
https://www.thno.org/v16p0516.htm
cellular and tissue sources, as well as extracellular vesicle mimetics; and (iii) bioactive substances, including oxygen-releasing
https://www.thno.org/v02p0541.htm
method In vitro (HUVECs) The system allows VEGF encapsulation and bioactive protein release up to
https://www.thno.org/v10p9100.htm
Feng S, Wang S, Fan M, Jin W, Li X. et al . Production of bioactive recombinant human myeloid-derived
Exosomes-mediated Transfer of miR-125a/b in Cell-to-cell Communication: A Novel Mechanism of Genetic
https://www.thno.org/v10p7561.htm
cell-to-cell communication via transferring encapsulated cargoes, such as miRNAs, proteins and bioactive lipids [ 11 , 22 , 23